
AnaGain™ Nu: a clinically proven botanical ingredient to reduce hair loss
In the world of hair health, more and more people are looking for solutions that are not only effective but also natural, safe, and backed by science. At Modesta Cassinello, we have carefully selected each ingredient in our Hair Boost formula, and one of the key players is AnaGain™ Nu.
Why did we choose it? Because it offers a unique combination: plant-based origin, clinical evidence, and visible results. This nutraceutical is clinically proven as a dietary supplement to slow down hair loss and improve hair density from within.
What does AnaGain™ Nu mean?
AnaGain™ is a patented plant-based ingredient specifically developed to stimulate hair growth. It is important to distinguish between its topical use, simply called AnaGain™, and its oral form marketed as AnaGain™ Nu.
AnaGain™ vs AnaGain™ Nu, what's the difference?
- AnaGain™ Nu is the version developed for oral use: it is water-soluble, taste-neutral, and clinically validated as a nutraceutical in food supplements. It is a key ingredient for caring for your hair from within without the need for topical application.
- AnaGain™ is the version for cosmetic use, also widely used in cosmetic formulations for hair care such as serums and conditioners.
What is AnaGain™ Nu?
AnaGain™ Nu is a key ingredient in effective hair supplements, derived from edible organic pea sprouts (Pisum sativum L.), it is rich in phytonutrients, biotin, L-arginine, and isoflavones. These sprouts, grown hydroponically under controlled conditions, have a high concentration of secondary plant compounds that protect the plant and now also your hair follicle. It is also a plant-based alternative to traditional hair loss treatments.
What are phytonutrients?: Phytonutrients or phytochemicals are compounds found in plants that, although not considered essential nutrients like vitamins or minerals, have been shown to offer health benefits to humans.
Why is it key for hair health?
Hair loss is not just an aesthetic issue; it affects emotional well-being and can have diverse causes such as stress, hormonal imbalances, nutritional deficiencies, environmental exposure... All of these promote a pro-oxidant and pro-inflammatory environment in the follicle, which can lead to a deregulation of the hair follicle cycle.
Hair cycle: a delicate balance
Hair grows in three phases:
1. Growth phase or Anagen Phase: 85-90% of hair is in this phase. During this phase, not only the hair shaft grows, but also most of the epithelial compartments of the hair follicle that are inside 4 mm from the scalp. There is great cellular activity and keratinization of the germinal matrix cells that ascend, becoming hair.
This phase is the phase of the cycle with the highest metabolic activity and therefore the most vulnerable to aggressions.
Did you know that the duration of this phase determines the maximum length of your hair?: This phase is genetically determined, but external or internal factors can stop it.
2. Transition phase or Catagen Phase: In this phase, hair growth stops because cells stop dividing and the follicle enters an involution process. It represents 1% of all hair. The hair stops receiving nutrients and the follicle prepares for the next phase. Duration 2-3 weeks.
3. Natural shedding phase or Telogen Phase: During this phase, the hair detaches.
Approximately 10% to 15% of hair is in this phase. At the end of this phase, the hair falls out and the cycle begins again with the anagen phase where new hair begins to grow. Duration 3-4 months.
When this balance is broken, the proportion of hairs in the telogen phase increases compared to the anagen phase, diffuse hair loss appears. And this is where AnaGain™ Nu acts as a hair growth stimulant.

Clinical evidence: measurable results
An independent clinical study carried out by the Skin Test Institute (Neuchâtel, Switzerland) showed that daily supplementation with 100 mg of AnaGain™ Nu for 2 months achieved:
- A significant reduction in the number of fallen hairs at 28 days (-33.9%).
- An even greater improvement after 56 days of use (-37.1%).
- In addition, 86% of participants noticed a visible improvement, and 76% expressed their desire to continue the treatment.
How does AnaGain™ Nu work?
AnaGain™ Nu, the oral version of the ingredient, is clinically proven to reduce hair loss and promote hair density from within.
It activates the anagen phase by promoting the proliferation of keratinocytes and also stimulating the dermal papilla to induce new hair growth. In addition, thanks to its antioxidant and anti-inflammatory action, it protects the scalp against factors that alter the hair cycle such as stress, inflammation, or cellular aging.
Clinical evidence for AnaGain™ Nu focuses on its visible results in greater density and less hair loss after continuous oral consumption.
Stronger hair, with greater vitality and density, from within.
Why do we include it in Hair Boost?
Hair Boost by Modesta Cassinello is not just another hair supplement. It is a formula developed with pharmaceutical and nutritional criteria, designed to act from within, where the hair cycle begins.
We include AnaGain™ Nu because its efficacy is backed by clinical studies in people with active hair loss. Daily supplementation has been shown to reduce hair loss by up to 37% after two months, visibly improving hair density and user satisfaction. We include this active ingredient in our formula at the same concentration used in the study, 100 mg.
Its differential value:
- 100% plant-based and organic origin: edible pea sprouts grown under controlled conditions.
- Scientifically proven oral formula: effective even without prior nutritional deficiencies.
- Rich in other nutrients biotin, L-arginine, and isoflavones.
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Perfect synergy with other active ingredients in our formula, which optimize the hair follicle environment to promote healthy, strong, and resistant growth.

Who is it for?
Hair Boost with AnaGain™ Nu is designed for:
- Women with weakened, fine hair, or progressive loss.
- Women in perimenopause or menopause who notice changes in their hair texture.
- Men in initial stages of hair loss due to stress, age, or hormonal changes.
- People who want to address seasonal or diffuse hair loss.
- Those seeking a natural, safe, and evidence-based alternative to improve hair health from within.
Important: In cases of persistent hair loss over time or progressive thinning of the hair fiber, it is essential to consult a specialist (dermatologist or trichologist). Only an appropriate clinical diagnosis will allow identification of the underlying causes and establishment of the most effective treatment in each case.
Hair Boost with AnaGain™ Nu: an effective formula to curb hair loss
At Modesta Cassinello, we are committed to Hair Boost, a clean, effective, and scientifically proven formula to promote a healthy scalp and hair growth. In addition to zinc, selenium, and vitamin E, we incorporate AnaGain™ Nu as a main active ingredient with studies demonstrating it curbs hair loss. Hair Boost is a real, natural, and safe solution to strengthen your hair from within.

Each article is backed by the expertise of our founder and CEO Dr. Modesta Cassinello, Doctor in Pharmacy and Diploma in Nutrition, committed to excellence in skin and hair care.

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